Diffuse Large B-Cell Lymphoma (DLBCL) Stories
Diffuse large b-cell lymphoma (DLBCL) is a common subtype of b-cell non-Hodgkin’s lymphoma, and is usually an aggressive cancer, one that progresses quickly.
Explore below to hear DLBCL patient stories and experiences. Our community members share their first symptoms of non-Hodgkin’s lymphoma, how they made treatment decisions, their entire treatment experience, recovery, and navigating quality of life issues.
DLBCL General Information
Commonly reported first symptoms of non-Hodgkin’s lymphoma in general include, but are not limited to:
- Swollen or enlarged lymph nodes
- Sudden and/or acute weight loss
- Appetite loss
- Night sweats
- Extreme fatigue
- Unexplained itchiness
Patient Stories on Symptoms
Explore patient stories on the first signs they knew something was wrong.
The most common treatment for DLBCL is a four-drug chemotherapy regimen, known as CHOP:
- C – Cyclophosphamide
- H – Doxorubicin Hydroxydaunomycin
- O – Vincristine Sulfate (Onvocin)
- P – Prednisone
Oftentimes, it’s combined with a monoclonal antibody known as rituximab or Ritxuan, known altogether as R-CHOP.
One alternative chemo regimen is dose-adjusted or DA-R-EPOCH:
- R – Rituximab
- E – Etoposide Phosphate
- P – Prednisone
- O – Vincristine Sulfate (Oncovin)
- C – Cyclophosphamide
- H – Doxorubicin Hydrochloride (Hydroxydaunorubicin)
Patient Stories on Treatments
Hear from patients on their R-EPOCH chemotherapy regimen experiences.
DLBCL Patient Stories
Hear From DLBCL Patients
Stephanie Chuang, founder of The Patient Story, celebrates five years of being cancer-free. She shares a very personal video diary with the top lessons she learned since the Non-Hodgkin lymphoma diagnosis.
Robyn S., Stage 2E Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)
Symptoms: Enlarged lymph nodes
Treatments: Chemotherapy: R-CHOP, R-ICE, intrathecal, BEAM; autologous stem cell transplant, head and neck radiation, CAR T-cell therapy
Richard P., Relapsed/Refractory Follicular Lymphoma & DLBCL
1st Symptoms of relapse: Swelling in leg, leg edema Treatment:1st line - R-CHOP chemotherapy, 2nd line - clinical trial of venetoclax-selinexor
Shahzad's CAR T Story
Cancer details: Refractory non-Hodgkin lymphoma, stage 4
1st Symptoms: Extreme fatigue
Treatment: R&B, R-ICE, R-EPOCH, CAR T-cell therapy (cell-based gene therapy)
FDA approved: October 2017
Erin R., DLBCL & Burkitt Lymphoma, Stage 4
Cancer details: Characteristics of both subtypes
1st Symptoms: Lower abdominal pain, blood in stool, loss of appetite
Treatment: Chemotherapy (Part A: R-CHOP, HCVAD, Part B: Methotrexate, Rituxan, Cytarabine)
Quality of Life Topics
Fertility preservation is not always an option for cancer patients, but when treatments like chemotherapies are involved, our community members recommend that you ask about it. This includes procedures like egg retrieval and freezing, as well as sperm banking.
Read patient stories on how they approached fertility preservation after a cancer diagnosis.
A detailed look at the egg harvesting and retrieval from a cancer patient who went through the process before starting chemotherapy.
Hair loss, often experienced after chemotherapy, is one of the first things that comes to mind for many patients when they first hear a cancer diagnosis.
Patients describe on how they managed through losing their hair after cancer treatments.
Trying to deal with a cancer diagnosis is overwhelming enough, but for many patients and their families, there’s the added stress of trying to figure out how to pay for cancer treatment.
Details on how Medicare can help cover (some) cancer-related costs.
Hear more from an expert on how patients and caregivers can approach issues like insurance and paying for treatment.
Dealing with emotional and mental stress
Read how patients worked through the anxiety of waiting for results from tests and scans, known as “scanxiety.”
Read on for answers from real cancer patients about how can you navigate the feelings that come along with hospital stays.