Myeloproliferative Neoplasms (MPNs) Patient Stories

Myeloproliferative Neoplasms (MPNs) Patient Stories & Specialist Interviews

Myeloproliferative neoplasms, also referred to commonly as “MPNs,” comprise a group of diseases caused by the bone marrow overproducing red blood cells, white blood cells, or platelets.

Three of the most common types of MPNs are essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF).

Explore below to read and watch in-depth MPN patient stories and get access to top MPN specialists, who detail the latest on emerging MPN treatments and clinical trials.

MPN Patient Stories

Myelofibrosis


Andrew S.



1st Symptoms: Nosebleeds (unrelated) led to blood work, revealing high WBCs



Treatment: Clinical trial, Gazyva (obinutuxumab) and steroids, Jakafi (ruxolitinib), Inrebic (fedratinib), Reblozyl (luspatercept)

Mary L.



Diagnosis: Myelofibrosis (MPN)
1st Symptoms: Fatigue, extreme dizziness (later diagnosed as vertigo)
Treatment: Pegasys, hydroxyurea (current)

MPN Specialist Conversations


Srdan Verstovsek, MD, PhD



Role: Director, Clinical Research Center for MPNs at MD Anderson; Section Chief, MPNs; Prof., Dept. of Leukemia
Focus: Myeloproliferative neoplasms (MPN)
Institution: MD Anderson

Ruben Mesa, MD



Role: Executive Director, Mays Cancer Center; Prof. of Medicine
Focus: Myeloproliferative neoplasms (MPN)
Institution: UT Health San Antonio MD Anderson

Myeloproliferative Neoplasm FAQs

Myelofibrosis

Explore myelofibrosis

Myelofibrosis is a rare cancer of the bone marrow. Learn more about myleofibrosis symptoms, diagnosis, treatment and more.

Polycythemia Vera

Explore polycythemia vera

Polycythemia vera (PV) is a rare, chronic blood disorder. Learn more about polycythemia vera symptoms, diagnosis, treatment and more.

Essential Thrombocythemia

Explore essential thrombocythemia

Essential thrombocythemia (ET) is a rare form of blood cancer in which the bone marrow overproduces platelets. Learn more about essential thrombocythemia symptoms, diagnosis, treatment and more.