Bleomycin Side Effects & Stories | The Patient Story

Bleomycin Side Effects & Stories

Read patient experiences with the antibiotic drug, bleomycin, used in chemotherapy. For medical information on bleomycin, check with your doctor.

Background: Bleomycin is usually given by injection to treat several cancers, including (but not limited to): cervical, Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and testicular cancers1.


Bleomycin Side Effects

Some of the most common reported side effects from Bleomycin include, but are not limited to2:

  • Itching
  • Rash
  • Nausea
  • Vomiting
  • Weight loss
  • Changes to skin color

Patient Stories by Side Effect

Hodgkin’s Lymphoma Stories

“I got ABVD chemo for the first two cycles, which was four rounds. For the rest of the eight treatments, it was just the AVD.

They took out the B drug (bleomycin) because my PET scan after the first four treatments showed that I had no evidence of disease. They were able to take out the bleomycin since it can be hard on your lungs.”

→ Lia Sartorio, Read Full Story

“I think the nausea got a little better without the bleomycin, but it was still pretty killer. One less medicine is always a relief.”

→ Mara Thrasher, Read Full Story

“My doctor is very much into clinical trials and research at a global scale. When I was going through treatment, he had just learned of a study that realized that if you pull bleomycin, the B in “ABVD,” halfway through your infusion schedule, it really has no effect on the remission rate.”

→ CC Webster, Read Full Story

“What impressed me about my new oncologist’s unique approach to this standard treatment was its dynamicity. It involved a mid-treatment PET/CT scan to determine if it was possible to downgrade the chemo regimen from the classic ABVD to a less intense AVD, thereby dropping the “B” (bleomycin) after just one of the six cycles.

Bleomycin is one of those nasty chemo drugs that can have detrimental long-term effects on your lungs. The less of it your body has to endure, the better, and his treatment approach was very mindful of that.”

→ Nicole Massoumi, Read Full Story

Testicular Cancer Stories

“Typically, anyone who is diagnosed with testicular cancer and needs chemo goes on the BEP regimen. Each cycle takes three weeks, and it’s three cycles, so it’s nine weeks.

However, after the first cycle, I had complications with the Bleomycin in my lungs. That’s not uncommon. Since I had those complications, they had to stop that particular chemo drug and continue with an extra two rounds of the EP.”

→ Hugo Toovey, Read Full Story


All Patient Stories with Bleomycin

Hodgkin’s Lymphoma Stories: Stage 4 | Nicole Massoumi

Nicole Massoumi, Hodgkin's, Stage 4



Cancer details: Staged 2 then 4 after second opinion
1st Symptoms: Extreme fatigue, persistent itching on lower half of legs
Treatment: 6 cycles (12 infusions) chemo, ABVD then AVD (dropped bleomycin)
...
Hodgkin’s Lymphoma Stories: Mara Thrasher, Stage 2BX (Bulky Disease) | The Patient Story

Mara Thrasher, Stage 2BX (Bulky)



1st Symptoms: Shortness of breath, back pains, daily migraines
Treatment: 3 rounds of ABVD, 3 rounds AVD, Radiation
Topics: Self-advocacy, mental health
...
Hodgkin’s Lymphoma Stories: Stage 3B, Classical | Erica’s Story

Erica Hernandez, Hodgkin's, Stage 3B



Cancer details: Staged at 3B
1st Symptoms: Intense itchiness, fatigue, night sweats, weight loss
Treatment:ABVD chemotherapy, 6 cycles (12 infusions)
...
Testicular Cancer Stories: Embryonal Carcinoma, Non-Seminoma, Stage 2B | Hugo Toovey

Hugo Toovey, Non-Seminoma, Stage 2B



Age at Diagnosis: 21
1st Symptoms:
Pea-sized lump on right testicle
Treatment: Surgical removal of right testicle, lymph node resection, chemotherapy

...
Testicular Cancer Stories: Non-Seminoma Germ Cell, Stage 3C | Steve Lynch

Steve Lynch, Non-Seminoma, Stage 4



Age at Diagnosis: 25
1st Symptoms:
Grape-sized tumor on neck; hip and pelvis pain; ultrasound revealed tumor on right testicle
Treatment:
Chemotherapy (BEP), removal of right testicle, lymph node resection (RPLND), and tumor dissection in the neck
...
Hodgkin’s Lymphoma Stories: Classical, Nodular Sclerosis, Stage 4A | Lia Sartorio

Lia Sartorio, Nodular Sclerosis, Stage 4A



Cancer details: Most common and most treatable form of Hodgkin's lymphoma
1st Symptoms:
Extreme lower back pain
Treatment:
ABVD chemotherapy
...
Hodgkin’s Lymphoma Stories: Stage 4, Classical | CC’s Story

CC Webster, Hodgkin's, Stage 4



Cancer details: Diagnosed at 29, misdiagnosed as mono
1st Symptoms: Achiness, extreme fatigue, reactive rash on chest and neck. Later: chills, night sweats
Treatment: ABVD chemotherapy (6 cycles)
...
Hodgkin’s Lymphoma Stories: Stage 3A, Refractory to Gray Zone Lymphoma | Kayla Tremblett

Kayla Tremblett, Hodgkin's, Stage 3A



Cancer details: Possibly misdiagnosed the first time; later diagnosed as grey zone lymphoma
1st Symptoms: Pulled muscle in chest
Treatment: ABVD chemo, radiation, high-dose chemo, stem cell transplant
...
Hodgkin’s Lymphoma Stories: Classical, Stage 3, Relapse | Tylere Presley

Tylere Presley, Hodgkin, Stage 3



Cancer details: Mother is a nurse practitioner; suspected cancer
1st Symptoms: Swollen lymph nodes in neck
Treatment: Clinical trial; Chemotherapy, BMT
...
Hodgkin’s Lymphoma Stories: Jade Blouin, Classical, Stage 2X (Bulky Disease) | The Patient Story

Jade Blouin, Hodgkin, Stage 2X



Cancer details: Diagnosed at 21 years old
1st Symptoms: Itchy legs and feet
Treatment: ABVD chemotherapy (4 treatments), AVD (remaining treatments)
...
Hodgkin’s Lymphoma Stories: Classical, Stage 2BX, Bulky Disease | Stephanie Ou

Stephanie Ou, Hodgkin's, Stage 2B



Cancer details: Stage 2 with bulky disease
1st Symptoms: Shortness of breath, dry cough
Treatment: Stanford V chemotherapy (12 weeks, 1 infusion each week), radiation (20 days)
...
Hodgkin’s Lymphoma Stories: Fabiola Lopez, Stage 2BX (Bulky Disease), Relapse | The Patient Story

Fabiola Lopez, Hodgkin's, Stage 2BX



Cancer details: Stage 2 with bulky disease, relapsed after 1st chemo. Remission after 2nd chemo & bone marrow transplant
1st Symptoms: Shortness of breath, dry cough, fatigue
Treatment: ABVD chemo (6 cycles), IGEV chemo, bone marrow transplant, BEAM chemo, brentuximab
...
Hodgkin’s Lymphoma Stories: Wade Winslow, Classical, Stage 2A, AYA Cancer | The Patient Story

Wade Winslow, Hodgkin's, Stage 2A



Cancer details: Diagnosed at 18 years old
1st Symptoms: Enlarged lymph nodes (around neck), diagnosed at 18 years old
Treatment: ABVD chemotherapy (2 cycles), AVD chemotherapy (4 cycles)
...
Hodgkin’s Lymphoma Stories: Lauren Chiarello, Stage 2A, Relapse, Nodular Sclerosis | The Patient Story

Lauren Chiarello, Hodgkin's, Stage 2A



Cancer details: Diagnosed at 23 years old with nodular sclerosis, relapsed after 6 months of 1st-line treatment
1st Symptoms: Itchy body, enlarged lymph node over collar bone
Treatment: ABVD chemotherapy and ICE, radiation, and stem cell transplant for relapse
...
Hodgkin’s Lymphoma Stories: Helicon Kuan, Classical, Stage 2A | The Patient Story

Helicon Kuan, Hodgkin's, Stage 2A



Cancer details: Found lymphoma cells in adenoid tissue
1st Symptoms: Difficulty breathing with blockage in nose, surgery to remove tissue resulted in discovery of Hodgkin lymphoma cells
Treatment: ABVD chemotherapy (4 cycles), radiation (20 sessions)
...
Hodgkin’s Lymphoma Stories: Logan Agee, Stage 2A, Adolescent (AYA) Cancer | The Patient Story

Logan Agee, Hodgkin's, Stage 2A



Cancer details: Diagnosed at age 15
1st Symptoms:
Lump in neck & fatigue
Treatment:
4 cycles of ABVE-PC chemo
...
Hodgkin’s Lymphoma Stories: Lani Skelley, Classical, Stage 2 | The Patient Story

Lani Skelley, Hodgkin's, Stage 2



Cancer details: Tumor pressing on heart
1st Symptoms: Appendicitis led to CT scan that found tumor
Treatment: ABVD chemotherapy, 7 cycles
...
Hodgkin’s Lymphoma Stories: Danielle Doyle, Classical, Stage 2 | The Patient Story

Danielle Doyle, Hodgkin's, Stage 2



Cancer details: Diagnosed at age 25
1st Symptoms: Swollen lump on right side of neck/chest area, continued to grow
Treatment: ABVD chemotherapy (3 cycles = 6 infusions)
...
Hodgkin’s Lymphoma Stories: Nodular Sclerosis, Stage 1B | Madi’s Story

Madi Jones, Hodgkin's, Stage 1B



Cancer details: Most common and most treatable form of Hodgkin lymphoma
1st Symptoms:
Shortness of breath
Treatment:
3 rounds (6 infusions) of ABVD chemo
...

References

1. Bleomycin. Medline Plus, U.S. National Library of Medicine, 15 Aug 2011, https://medlineplus.gov/druginfo/meds/a682125.html.

2. Brandt, Josiah P.; Gerriets,Valerie. “Bleomycin.”Bookshelf, U.S. National Library of Medicine, 18 Sept 2020, https://www.ncbi.nlm.nih.gov/books/NBK555895/.