Relapsed/Refractory Cancer Stories | The Patient Story

Relapsed/Refractory Cancer Stories

The journey for people whose cancers have relapsed or who don’t respond to first-line treatment looks very different. Called relapsed or refractory, this often requires second-line or third-line treatment.

Hear from patients and families who’ve been through some of the newest applications of drugs and treatments giving hope to those who’ve relapsed or who are refractory.

Relapsed/Refractory Patient Stories

Hodgkin’s Lymphoma Stories: Stage 2A, Relapse, Nodular Sclerosis | Lauren’s Patient Story

Lauren C., Hodgkin's, Stage 2A

Cancer details: Diagnosed at 23 years old with nodular sclerosis, relapsed after 6 months of 1st-line treatment
1st Symptoms: Itchy body, enlarged lymph node over collar bone
Treatment: ABVD chemotherapy and ICE, radiation, and stem cell transplant for relapse
Hodgkin’s Lymphoma Stories: Stage 2BX, Relapse | Fabiola’s Patient Story

Fabiola L., Hodgkin's, Stage 2BX

Cancer details: Stage 2 with bulky disease, relapsed after 1st chemo. Remission after 2nd chemo & bone marrow transplant
1st Symptoms: Shortness of breath, dry cough, fatigue
Treatment: ABVD chemo (6 cycles), IGEV chemo, bone marrow transplant, BEAM chemo, brentuximab
Hodgkin’s Lymphoma Stories: Classical, Stage 3, Relapse | Tylere’s Story

Tylere P., Hodgkin, Stage 3

Cancer details: Mother is a nurse practitioner; suspected cancer
1st Symptoms: Swollen lymph nodes in neck
Treatment: Clinical trial; Chemotherapy, BMT
Hodgkin’s Lymphoma Stories: Stage 3A, Refractory to Gray Zone Lymphoma | Kayla’s Story

Kayla T., Hodgkin's, Stage 3A

Cancer details: Possibly misdiagnosed the first time; later diagnosed as grey zone lymphoma
1st Symptoms: Pulled muscle in chest
Treatment: ABVD chemo, radiation, high-dose chemo, stem cell transplant
Leukemia Story: Acute Lymphoblastic Leukemia (ALL), Relapse | Casey’s Story

Casey H., Acute Lymphoblastic Leukemia (ALL)

1st symptoms:
Lump on throat, extreme fatigue, shortness of breath, bruising easily
Chemo, immunotherapy, radiation, stem cell transplant
CAR T-Cell Therapy Stories: Refractory Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma

Shahzad's CAR T Story

Cancer details: Refractory non-Hodgkin lymphoma, stage 4
1st Symptoms: Extreme fatigue
Treatment: R&B, R-ICE, R-EPOCH, CAR T-cell therapy (cell-based gene therapy)
FDA approved: October 2017
Non-Hodgkin’s Lymphoma Stories: Primary Mediastinal B-Cell Lymphoma, Relapsed, CAR T-Cell Therapy

Sonia S., Primary Mediastinal (PMBCL), Relapse, CAR T-Cell Therapy

1st Symptoms: Chest pain, superior vena cava syndrome (SVCS); persistent, dry coughs, headaches
Treatment: (1st Line) R-CHOP chemotherapy, 6 cycles (2nd Line) R-ICE Chemotherapy (3rd Line) CAR T-cell therapy
Hodgkin’s Lymphoma Stories: Stage 2B, Relapse, Transplant| Moe’s Patient Story

Moe C., Hodgkin's, 2B, Relapse

Cancer details: Diagnosed at 19, relapsed before remission
1st Symptoms: Fatigue, weight loss, night sweats
Treatment: ABVD chemo, DHAP chemo, MINE-R chemo, splenectomy, autologous bone marrow transplant
Lymphoma Diagnosis Stories | The Patient Story

Richard P., Relapsed/Refractory Follicular Lymphoma & DLBCL

1st Symptoms of relapse: Swelling in leg, leg edema Treatment:1st line - R-CHOP chemotherapy, 2nd line - clinical trial of venetoclax-selinexor